NaturalProductMech

griseusin A

naturalproductmech:mibig-cfb019a5cc MINTED SEEDED

Structure

Standard InChIKeyDKQCCDMPFPKSEP-KSOWGMSTSA-N
SMILESC[C@@H]1C[C@H]([C@H]([C@@]2(O1)C3=C([C@@H]4[C@H](O2)CC(=O)O4)C(=O)C5=C(C3=O)C(=CC=C5)O)O)OC(=O)C
Stereochemistryfully defined
Cross-referencespubchem:16102131

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces griseus
NCBITaxon:1911
SOURCE_ASSERTION mibig:BGC0000231 PMID:8169211

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces griseus
NCBITaxon:1911
LOTUS DOI:10.1128/JB.176.9.2627-2634.1994
Streptomyces griseus
NCBITaxon:1911
LOTUS DOI:10.7164/ANTIBIOTICS.29.7

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000231 Streptomyces griseus
NCBITaxon:1911
CLUSTER_UNSTATED genbank:X77865.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000231MIBIG5

This page is generated from data/natural_products/polyketides/griseusin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.