hygrocin B
naturalproductmech:mibig-1881debca3 MINTED SEEDED
Structure
| Standard InChIKey | YCXQGZJYZGFQSB-AMMLVUSNSA-N |
|---|---|
| SMILES | CCC1CCC(=O)C2=C(O)C(C)=CC3=C2C(=O)C2=C(NC(=O)C=C[C@]2(C)C(=O)O[C@@H](C)[C@@H](O)\C=C\1)C3=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA011351, pubchem:5326384 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. LZ35 NCBITaxon:1245024 |
SOURCE_ASSERTION | mibig:BGC0000075 | PMID:24501776 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/NP400474S |
| Streptomyces hygroscopicus NCBITaxon:1912 |
LOTUS | DOI:10.1016/J.GENE.2014.05.053 |
| Streptomyces hygroscopicus NCBITaxon:1912 |
LOTUS | DOI:10.1021/NP050272L |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000075 | Streptomyces sp. LZ35 NCBITaxon:1245024 |
CLUSTER_UNSTATED | genbank:JX504844.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000075 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/hygrocin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.