NaturalProductMech

kinamycin

naturalproductmech:mibig-7542267beb MINTED SEEDED

Structure

Standard InChIKeyXNBGMEGJUYHLRB-OLKYXYMISA-N
SMILESCC(=O)O[C@@H]1[C@H](C2=C([C@H]([C@@]1(C)OC(=O)C)OC(=O)C)C(=C3C2=C(C4=CC=CC(=O)C4=C3O)[O-])[N+]#N)O
Stereochemistryfully defined
Cross-referencespubchem:161863

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces murayamaensis
NCBITaxon:224537
SOURCE_ASSERTION mibig:BGC0000236 PMID:9531987

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces murayamaensis
NCBITaxon:224537
LOTUS DOI:10.7164/ANTIBIOTICS.42.179
Streptomyces murayamaensis
NCBITaxon:224537
LOTUS DOI:10.7164/ANTIBIOTICS.51.50

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000236 Streptomyces murayamaensis
NCBITaxon:224537
CLUSTER_UNSTATED genbank:AH012623.2

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000236MIBIG5

This page is generated from data/natural_products/polyketides/kinamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.