NaturalProductMech

kinanthraquinone B

CHEBI:167576 EXACT SEEDED

A monohydroxyanthraquinone that is anthraquinone in which the hydrogen atoms at positions 1, 2, 5 and 6 are replaced hydroxy, 3-methylbut-3-enoic acid, methoxy and methoxy groups, respectively. It is a natural product isolated from Streptomyces sp. SN-593.

Structure

Standard InChIKeyUBMNDGOTJSQUMP-NTMALXAHSA-N
SMILESCOC1=C(OC)C2=C(C=C1)C(=O)C1=C(C=CC(/C=C(/C)CC(=O)O)=C1O)C2=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA033065

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. SN-593
NCBITaxon:659352
SOURCE_ASSERTION mibig:BGC0002383 PMID:33590007

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1093/BBB/ZBAA082
Streptomyces sp. SN-593
NCBITaxon:659352
CHEBI PMID:33590007

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002383 Streptomyces sp. SN-593
NCBITaxon:659352
CLUSTER_DEMONSTRATED genbank:AP018365.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002383MIBIG3
CHEBI:167576CHEBI3-star

This page is generated from data/natural_products/polyketides/kinanthraquinone-b.yaml, which is generated from the committed inventories. Neither is edited by hand.