kosinostatin
naturalproductmech:mibig-f194993c57 MINTED SEEDED
Structure
| Standard InChIKey | IWQFYWITNQDEGF-CCCCNFCVSA-N |
|---|---|
| SMILES | C[C@H]1[C@@]([C@@H](C[C@@H](O1)O[C@@H]2C3=C([C@@H]4C[C@]2(OC45C=C6CCN=C6N5)C)C(=C7C(=C3)C(=O)C8=C(C7=O)C=CC=C8O)O)O)(C(=O)C)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:102302126, npatlas:NPA05118 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Micromonospora sp. TP-A0468 NCBITaxon:1182970 |
SOURCE_ASSERTION | mibig:BGC0001073 | PMID:23790490 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001073 | Micromonospora sp. TP-A0468 NCBITaxon:1182970 |
CLUSTER_UNSTATED | genbank:JN038178.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001073 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/kosinostatin.yaml, which is generated from the committed inventories. Neither is edited by hand.