lankamycin
naturalproductmech:mibig-2436e2aa24 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | JQMACDQCTNFQMM-QAOHEUSVSA-N |
|---|---|
| SMILES | [H][C@@]1(OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@H](OC(C)=O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](OC)[C@H]2O)[C@@H](C)C[C@](C)(O)C(=O)[C@H](C)[C@@H](OC(C)=O)[C@H]1C)[C@@H](C)[C@H](C)O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA08120, pubchem:122781 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces rochei NCBITaxon:1928 |
SOURCE_ASSERTION | mibig:BGC0000085 | PMID:12791134 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces spinichromogenes NCBITaxon:285519 |
LOTUS | DOI:10.1002/HLCA.19640470111 |
| Streptomyces rochei NCBITaxon:1928 |
LOTUS | DOI:10.1002/CBIC.201500393 |
| Streptomyces rochei NCBITaxon:1928 |
LOTUS | DOI:10.1038/S41598-019-47406-Y |
| Streptomyces rochei NCBITaxon:1928 |
LOTUS | DOI:10.1046/J.1365-2958.2003.03523.X |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000085 | Streptomyces rochei NCBITaxon:1928 |
CLUSTER_UNSTATED | genbank:AB088224.2 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000085 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/lankamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.