NaturalProductMech

lasalocid

naturalproductmech:mibig-73ba44dafe MINTED SEEDED

Structure

Standard InChIKeyRDHDUYAKDYQPEW-UHFFFAOYSA-M
SMILESCCC(C1C(CC(O1)(CC)C2CCC(C(O2)C)(CC)O)C)C(=O)C(C)C(C(C)CCC3=C(C(=C(C=C3)C)O)C(=O)[O-])O.[Na+]
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:2724110

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces lasaliensis
NCBITaxon:324833
SOURCE_ASSERTION mibig:BGC0000086 PMID:18710235
Streptomyces lasaliensis
NCBITaxon:324833
SOURCE_ASSERTION mibig:BGC0000087 PMID:19025863

Occurrences 0

None cited.

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0000086 Streptomyces lasaliensis
NCBITaxon:324833
CLUSTER_UNSTATED genbank:AB449340.1
mibig:BGC0000087 Streptomyces lasaliensis
NCBITaxon:324833
CLUSTER_UNSTATED genbank:FM173265.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000086, BGC0000087. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000086MIBIG5
BGC0000087MIBIG5

This page is generated from data/natural_products/polyketides/lasalocid-2.yaml, which is generated from the committed inventories. Neither is edited by hand.