lipstatin
naturalproductmech:mibig-7c5b732cca MINTED SEEDED
Structure
| Standard InChIKey | OQMAKWGYQLJJIA-CUOOPAIESA-N |
|---|---|
| SMILES | CCCCCC[C@H]1[C@H](C[C@H](C\C=C/C\C=C/CCCCC)OC(=O)[C@H](CC(C)C)NC=O)OC1=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA016962, pubchem:6438672 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces toxytricini NCBITaxon:67369 |
SOURCE_ASSERTION | mibig:BGC0000382 | PMID:25239907 |
Occurrences 9
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces toxytricini NCBITaxon:67369 |
LOTUS | DOI:10.1007/S00253-010-2587-2 |
| Streptomyces toxytricini NCBITaxon:67369 |
LOTUS | DOI:10.1007/S00284-017-1420-X |
| Streptomyces toxytricini NCBITaxon:67369 |
LOTUS | DOI:10.1007/S12275-009-0135-5 |
| Streptomyces toxytricini NCBITaxon:67369 |
LOTUS | DOI:10.1007/S12275-011-1122-1 |
| Streptomyces toxytricini NCBITaxon:67369 |
LOTUS | DOI:10.1007/S13205-017-1049-2 |
| Streptomyces toxytricini NCBITaxon:67369 |
LOTUS | DOI:10.1074/JBC.M003094200 |
| Streptomyces toxytricini NCBITaxon:67369 |
LOTUS | DOI:10.2323/JGAM.60.106 |
| Streptomyces toxytricini NCBITaxon:67369 |
LOTUS | DOI:10.7164/ANTIBIOTICS.40.1081 |
| Streptomyces toxytricini NCBITaxon:67369 |
LOTUS | DOI:10.7164/ANTIBIOTICS.40.1086 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000382 | Streptomyces toxytricini NCBITaxon:67369 |
CLUSTER_UNSTATED | genbank:KJ872771.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000382 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/lipstatin.yaml, which is generated from the committed inventories. Neither is edited by hand.