lomaiviticin A
naturalproductmech:mibig-4b1562dcf5 MINTED SEEDED
Structure
| Standard InChIKey | VGDUHSQTOJRQNB-JGBUZTLDSA-N |
|---|---|
| SMILES | CC[C@@]1(OC2CC(OC)C(O)C(C)O2)[C@H](OC2CC(O)C(C(C)O2)N(C)C)C2=C(C3=C(C2=[N+]=[N-])C(=O)C2=C(O)C=CC(O)=C2C3=O)C(=O)[C@@H]1[C@H]1C(=O)C2=C([C@@H](O[C@H]3CC(O)[C@@H](C(C)O3)N(C)C)[C@@]1(CC)OC1CC(OC)C(O)C(C)O1)C(=[N+]=[N-])C1=C2C(=O)C2=C(O)C=CC(O)=C2C1=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA06818, pubchem:56841540 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, saccharide, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Salinispora pacifica NCBITaxon:351187 |
BGC_CHARACTERIZED | mibig:BGC0000240 | PMID:23649992 |
| Salinispora tropica CNB-440 NCBITaxon:369723 |
BGC_CHARACTERIZED | mibig:BGC0000241 | PMID:23649992 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Salinispora tropica NCBITaxon:168695 |
LOTUS | DOI:10.1002/CBIC.201300147 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000240 | Salinispora pacifica NCBITaxon:351187 |
CLUSTER_DEMONSTRATED | genbank:KF731828.1 |
| mibig:BGC0000241 | Salinispora tropica CNB-440 NCBITaxon:369723 |
CLUSTER_DEMONSTRATED | genbank:CP000667.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000240, BGC0000241. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000240 | MIBIG | 5 |
| BGC0000241 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/lomaiviticin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.