lomaiviticin E
naturalproductmech:mibig-3e651964d5 MINTED SEEDED
Structure
| Standard InChIKey | UUFARPZDPLRTPW-YHYZUSIDSA-N |
|---|---|
| SMILES | CC[C@@]1([C@H](C(=C2C(=CC3=C2C(=C4C(=O)C=CC(=O)C4=C3O)O)[C@H]1O[C@@H]5C[C@@H]([C@H]([C@@H](O5)C)N(C)C)O)O)[C@H]6C(=O)C7=C([C@H]([C@@]6(CC)O[C@H]8C[C@@H]([C@H]([C@@H](O8)C)OC)OC)O[C@@H]9C[C@@H]([C@H]([C@@H](O9)C)N(C)C)O)C(=[N+]=[N-])C1=C7C(=C2C(=O)C=CC(=O)C2=C1O)O)O[C@H]1C[C@@H]([C@H]([C@@H](O1)C)OC)OC |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA08789 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, saccharide, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Salinispora pacifica NCBITaxon:351187 |
BGC_CHARACTERIZED | mibig:BGC0000240 | PMID:23649992 |
| Salinispora tropica CNB-440 NCBITaxon:369723 |
BGC_CHARACTERIZED | mibig:BGC0000241 | PMID:23649992 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Salinispora pacifica NCBITaxon:351187 |
LOTUS | DOI:10.1021/JA3074984 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000240 | Salinispora pacifica NCBITaxon:351187 |
CLUSTER_DEMONSTRATED | genbank:KF731828.1 |
| mibig:BGC0000241 | Salinispora tropica CNB-440 NCBITaxon:369723 |
CLUSTER_DEMONSTRATED | genbank:CP000667.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000240, BGC0000241. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000240 | MIBIG | 5 |
| BGC0000241 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/lomaiviticin-e.yaml, which is generated from the committed inventories. Neither is edited by hand.