macbecin
naturalproductmech:mibig-0075dfbf0a MINTED SEEDED
Structure
| Standard InChIKey | PLTGBUPHJAKFMA-RCZMPJGQSA-N |
|---|---|
| SMILES | CO[C@H]1C[C@H](C)[C@@H](OC)C2=CC(=O)C=C(NC(=O)\C(C)=C\C=C/[C@@H](C)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1OC)C2=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA019946 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Actinosynnema pretiosum subsp. pretiosum NCBITaxon:103721 |
BGC_CHARACTERIZED | mibig:BGC0000090 | PMID:18800759 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Nocardia NCBITaxon:1817 |
LOTUS | DOI:10.1271/BBB1961.46.1699 |
| Nocardia NCBITaxon:1817 |
LOTUS | DOI:10.7164/ANTIBIOTICS.33.199 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000090 | Actinosynnema pretiosum subsp. pretiosum NCBITaxon:103721 |
CLUSTER_DEMONSTRATED | genbank:EU827593.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000090 | MIBIG | 4 |
This page is generated from data/natural_products/polyketides/macbecin.yaml, which is generated from the committed inventories. Neither is edited by hand.