maduramicin
naturalproductmech:mibig-f79f7e1d44 MINTED SEEDED
Structure
| Standard InChIKey | RWVUEZAROXKXRT-VQLSFVLHSA-N |
|---|---|
| SMILES | CO[C@H]1C[C@@H](O[C@H]2C[C@H]([C@H]3O[C@](C)(O)[C@H](C)C[C@@H]3C)O[C@H]2[C@]2(C)CC[C@H]([C@]3(C)CC[C@]4(C[C@H](O)[C@@H](C)[C@@H]([C@@H](C)[C@@H]5O[C@](O)(CC(=O)O)[C@@H](C)[C@H](OC)[C@H]5OC)O4)O3)O2)O[C@@H](C)[C@@H]1OC |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA032771 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Actinomadura sp. NCBITaxon:1989 |
BGC_CORRELATED | mibig:BGC0002431 | PMID:31853778 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Actinomadura yumaensis NCBITaxon:111807 |
LOTUS | DOI:10.1021/AC00131A016 |
| Actinomadura yumaensis NCBITaxon:111807 |
LOTUS | DOI:10.7164/ANTIBIOTICS.40.94 |
| Nocardia NCBITaxon:1817 |
LOTUS | DOI:10.7164/ANTIBIOTICS.36.343 |
| Actinomadura NCBITaxon:1988 |
LOTUS | DOI:10.1007/S10295-019-02256-5 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002431 | Actinomadura sp. NCBITaxon:1989 |
CLUSTER_CORRELATED | genbank:MN272733.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002431 | MIBIG | 3 |
This page is generated from data/natural_products/polyketides/maduramicin.yaml, which is generated from the committed inventories. Neither is edited by hand.