maduropeptin
naturalproductmech:mibig-6ef560faa6 MINTED SEEDED
Structure
| Standard InChIKey | RUCAXECSYVMPPH-QFIHHIJXSA-N |
|---|---|
| SMILES | COC1=C2C(=C(C=C1)[C@H](CC(=O)N3C[C@H]3/C/4=C/C#C[C@H](O2)[C@]5([C@H](CC=C5C#C4)O)O)O)Cl |
| Stereochemistry | fully defined |
| Cross-references | pubchem:102505401 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Actinomadura madurae NCBITaxon:1993 |
SOURCE_ASSERTION | mibig:BGC0001008 | PMID:17918933 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Actinomadura madurae NCBITaxon:1993 |
LOTUS | DOI:10.1021/JA00099A071 |
| Actinomadura madurae NCBITaxon:1993 |
LOTUS | DOI:10.1021/JA073275O |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001008 | Actinomadura madurae NCBITaxon:1993 |
CLUSTER_UNSTATED | genbank:AY271660.2 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001008 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/maduropeptin.yaml, which is generated from the committed inventories. Neither is edited by hand.