NaturalProductMech

malleilactone

naturalproductmech:mibig-9aa382c5b9 MINTED SEEDED

Structure

Standard InChIKeyWCPYCTRXCHJSFX-SYXZMITDSA-N
SMILESCCCCCCC\C=C(/C)\C(\O)=C1/C=C(OC1=O)C(=O)CC
Stereochemistryfully defined
Cross-referencespubchem:136229184, npatlas:NPA013598

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Burkholderia thailandensis E264; ATCC 700388
NCBITaxon:271848
BGC_CHARACTERIZED mibig:BGC0001102 PMID:32314848

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Burkholderia mallei
NCBITaxon:13373
LOTUS DOI:10.1021/JA3052156
Burkholderia pseudomallei
NCBITaxon:28450
LOTUS DOI:10.1021/JA3052156

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001102 Burkholderia thailandensis E264; ATCC 700388
NCBITaxon:271848
CLUSTER_DEMONSTRATED genbank:CP000085.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001102MIBIG5

This page is generated from data/natural_products/polyketides/malleilactone.yaml, which is generated from the committed inventories. Neither is edited by hand.