NaturalProductMech

medermycin

naturalproductmech:mibig-d4a6687eb8 MINTED SEEDED

Structure

Standard InChIKeyNWPHOPMRDKFXFP-SIPAFCNMSA-N
SMILESC[C@@H]1[C@H]([C@@H](CC(O1)C2=CC3=C(C=C2)C(=O)C4=C(C3=O)[C@H](O[C@H]5[C@@H]4OC(=O)C5)C)N(C)C)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:3035536

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. AM-7161
NCBITaxon:221710
SOURCE_ASSERTION mibig:BGC0000245 PMID:12855716

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1099/MIC.0.26310-0

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000245 Streptomyces sp. AM-7161
NCBITaxon:221710
CLUSTER_UNSTATED genbank:AB103463.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000245MIBIG5

This page is generated from data/natural_products/polyketides/medermycin.yaml, which is generated from the committed inventories. Neither is edited by hand.