megalomicin A
naturalproductmech:mibig-55d5b3a5d6 MINTED SEEDED
Structure
| Standard InChIKey | LRWRQTMTYVZKQW-WWDNQWNISA-N |
|---|---|
| SMILES | CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)O)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O[C@H]4C[C@H]([C@H]([C@@H](O4)C)O)N(C)C)C)C)O)(C)O |
| Stereochemistry | fully defined |
| Cross-references | pubchem:31864 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Micromonospora megalomicea subsp. nigra NCBITaxon:136926 |
SOURCE_ASSERTION | mibig:BGC0000092 | PMID:10972798 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Micromonospora megalomicea NCBITaxon:136926 |
LOTUS | DOI:10.7164/ANTIBIOTICS.22.253 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000092 | Micromonospora megalomicea subsp. nigra NCBITaxon:136926 |
CLUSTER_UNSTATED | genbank:AF263245.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000092 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/megalomicin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.