meridamycin
naturalproductmech:mibig-96b3df2d52 MINTED SEEDED
Structure
| Standard InChIKey | DGKUOWHAUIWQTM-XRWXWOGSSA-N |
|---|---|
| SMILES | CC\C1=C/C[C@H](OC(=O)C2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H](CC[C@H]2C)C[C@H](O)[C@H](C)[C@@H](O)C[C@@H](O)C[C@H](O)\C(C)=C/[C@@H](C)CC(C)[C@@H]1O)C(\C)=C\[C@@H](C)[C@@H](C)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces violaceusniger NCBITaxon:68280 |
SOURCE_ASSERTION | mibig:BGC0001012 | PMID:17159202 |
| Streptomyces sp. NCBITaxon:1931 |
SOURCE_ASSERTION | mibig:BGC0001013 | PMID:17159202 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces violaceusniger NCBITaxon:68280 |
LOTUS | DOI:10.1099/MIC.0.29176-0 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001012 | Streptomyces violaceusniger NCBITaxon:68280 |
CLUSTER_UNSTATED | genbank:DQ885223.1 |
| mibig:BGC0001013 | Streptomyces sp. NCBITaxon:1931 |
CLUSTER_UNSTATED | genbank:DL080157.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001012, BGC0001013. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001012 | MIBIG | 3 |
| BGC0001013 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/meridamycin-2.yaml, which is generated from the committed inventories. Neither is edited by hand.