NaturalProductMech

midecamycin

naturalproductmech:mibig-8f1123b739 MINTED SEEDED

Structure

Standard InChIKeyDMUAPQTXSSNEDD-ZZHFWOCQSA-N
SMILESCCC(=O)O[C@@H]1[C@H](O[C@H](C[C@@]1(C)O)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2N(C)C)O)OC3C(CC(C(/C=C\C=C\CC(OC(=O)CC(C3OC)OC(=O)CC)C)O)C)CC=O)C)C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:6436158

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces mycarofaciens
NCBITaxon:1949
SOURCE_ASSERTION mibig:BGC0000096 patent:US7070980B2

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces fradiae
NCBITaxon:1906
LOTUS DOI:10.1007/S00253-004-1658-7
Streptomyces mycarofaciens
NCBITaxon:1949
LOTUS DOI:10.1111/J.1745-7270.2007.00265.X
Streptomyces mycarofaciens
NCBITaxon:1949
LOTUS DOI:10.1128/JB.174.15.5141-5144.1992

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000096 Streptomyces mycarofaciens
NCBITaxon:1949
CLUSTER_UNSTATED genbank:BD420675.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000096MIBIG5

This page is generated from data/natural_products/polyketides/midecamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.