misakinolide A
naturalproductmech:mibig-7369bf06d5 MINTED SEEDED
Structure
| Standard InChIKey | CNXAVQHYRALFDY-VIPNGKGCSA-N |
|---|---|
| SMILES | C[C@@H]1O[C@H](C[C@@H](C1)OC)CC[C@@H]([C@H](O)[C@@H]([C@H]2OC(=O)/C(=C/C[C@@H](C[C@H]3O[C@H](C[C@@H]([C@H]([C@H](C[C@H]([C@@H]([C@H](OC(=O)/C(=C/C[C@@H](C[C@H]4O[C@H](C[C@@H]([C@H]([C@H](C[C@H]([C@@H]2C)O)O)C)OC)CC=C4)O)/C)[C@H]([C@@H](O)[C@H](CC[C@@H]5O[C@H](C[C@H](C5)OC)C)C)C)C)O)O)C)OC)CC=C3)O)/C)C)C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:6441172 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Candidatus Entotheonella serta NCBITaxon:1652106 |
SOURCE_ASSERTION | mibig:BGC0001186 | PMID:29779656 |
Occurrences 7
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Theonella NCBITaxon:37504 |
LOTUS | DOI:10.1039/P19910002379 |
| Theonella NCBITaxon:37504 |
LOTUS | DOI:10.1246/CL.1986.1499 |
| Theonella swinhoei NCBITaxon:37505 |
LOTUS | DOI:10.1021/NP049721S |
| Theonella swinhoei NCBITaxon:37505 |
LOTUS | DOI:10.1021/NP050404A |
| Theonella swinhoei NCBITaxon:37505 |
LOTUS | DOI:10.1021/NP060229D |
| Theonella swinhoei NCBITaxon:37505 |
LOTUS | DOI:10.1021/NP060464W |
| Theonella swinhoei NCBITaxon:37505 |
LOTUS | DOI:10.1021/NP9905665 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001186 | Candidatus Entotheonella serta NCBITaxon:1652106 |
CLUSTER_UNSTATED | genbank:KR857273.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001186 | MIBIG | 4 |
This page is generated from data/natural_products/polyketides/misakinolide-a.yaml, which is generated from the committed inventories. Neither is edited by hand.