mithramycin
CHEBI:31856 EXACT SEEDED antimicrobial unspecified
Structure
| Standard InChIKey | CFCUWKMKBJTWLW-BKHRDMLASA-N |
|---|---|
| SMILES | C[C@@H]1[C@H]([C@@H](C[C@@H](O1)O[C@@H]2C[C@@H](O[C@@H]([C@H]2O)C)OC3=CC4=CC5=C(C(=O)[C@H]([C@@H](C5)[C@@H](C(=O)[C@H]([C@@H](C)O)O)OC)O[C@H]6C[C@H]([C@@H]([C@H](O6)C)O)O[C@H]7C[C@H]([C@H]([C@H](O7)C)O)O[C@H]8C[C@]([C@@H]([C@H](O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O |
| Stereochemistry | fully defined |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces argillaceus NCBITaxon:41951 |
BGC_CHARACTERIZED | mibig:BGC0000247 | PMID:8654997 |
Occurrences 8
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1248/CPB.48.575 |
| Streptomyces lividans NCBITaxon:1916 |
LOTUS | DOI:10.1007/S00253-017-8642-5 |
| Streptomyces plicatus NCBITaxon:1922 |
CHEBI | 10.1016/S1054-3589(08)60218-5 |
| Streptomyces nogalater NCBITaxon:38314 |
LOTUS | DOI:10.1039/B200444P |
| Streptomyces argillaceus NCBITaxon:41951 |
LOTUS | DOI:10.1016/0378-1119(96)00029-7 |
| Streptomyces argillaceus NCBITaxon:41951 |
LOTUS | DOI:10.1016/J.YMBEN.2013.10.002 |
| Streptomyces argillaceus NCBITaxon:41951 |
LOTUS | DOI:10.1021/NP980355K |
| Streptomyces argillaceus NCBITaxon:41951 |
LOTUS | DOI:10.1371/JOURNAL.PONE.0198145 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000247 | Streptomyces argillaceus NCBITaxon:41951 |
CLUSTER_DEMONSTRATED | genbank:X89899.2 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:31856 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000247 | MIBIG | 5 |
| CHEBI:31856 | CHEBI | 3-star |
This page is generated from data/natural_products/polyketides/mithramycin.yaml, which is generated from the committed inventories. Neither is edited by hand.