NaturalProductMech

monascorubrin

naturalproductmech:mibig-7b44dfec44 MINTED SEEDED

Structure

Standard InChIKeyIIPVSGPTPPURBD-HAOIVFDCSA-N
SMILESCCCCCCCC(=O)C1=C2C=C3C=C(OC=C3C(=O)[C@]2(C)OC1=O)\C=C\C
Stereochemistryfully defined
Cross-referencespubchem:12118084, npatlas:NPA02306

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Monascus pilosus
NCBITaxon:89488
SOURCE_ASSERTION mibig:BGC0000027 PMID:23504076
Talaromyces marneffei
NCBITaxon:37727
SOURCE_ASSERTION mibig:BGC0000099 PMID:25335861

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Monascus purpureus
NCBITaxon:5098
LOTUS DOI:10.1016/S0040-4020(01)99285-3
Monascus pilosus
NCBITaxon:89488
LOTUS DOI:10.1021/JF040199P

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0000027 Monascus pilosus
NCBITaxon:89488
CLUSTER_UNSTATED genbank:KC148521.1
mibig:BGC0000099 Talaromyces marneffei
NCBITaxon:37727
CLUSTER_UNSTATED genbank:HM070047.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000027, BGC0000099. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000027MIBIG4
BGC0000099MIBIG3

This page is generated from data/natural_products/polyketides/monascorubrin.yaml, which is generated from the committed inventories. Neither is edited by hand.