monodictyphenone
CHEBI:64398 EXACT SEEDED
A member of the class of benzophenones in which one phenyl group is substituted at positions 2 and 6 by hydroxy groups while the other is substituted at positions 2, 4, and 6 by hydroxy, methyl, and carboxy groups, respectively. First obtained from the fungal strain Monodictys putredinis, isolated from the inner tissue of a marine green alga, it was subsequently obtained from the fungus Aspergillus nidulans.
Structure
| Standard InChIKey | UMNWQJSVQOCNEM-UHFFFAOYSA-N |
|---|---|
| SMILES | CC1=CC(C(O)=O)=C(C(=O)C2=C(O)C=CC=C2O)C(O)=C1 |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA016280, pubchem:16114922 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
BGC_CHARACTERIZED | mibig:BGC0000101 | PMID:19448638 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Monodictys putredinis NCBITaxon:2075174 |
LOTUS | DOI:10.1021/NP060505O |
| Monodictys putredinis NCBITaxon:2075174 |
LOTUS | DOI:10.1021/NP060505O.S001 |
| Monodictys putredinis NCBITaxon:2075174 |
LOTUS | DOI:10.1021/NP800392W |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000101 | Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
CLUSTER_DEMONSTRATED | genbank:BN001308.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000101 | MIBIG | 5 |
| CHEBI:64398 | CHEBI | 3-star |
This page is generated from data/natural_products/polyketides/monodictyphenone.yaml, which is generated from the committed inventories. Neither is edited by hand.