NaturalProductMech

mycalamide A

naturalproductmech:mibig-779317a78d MINTED SEEDED

Structure

Standard InChIKeyIJASURGZDJYQGF-UBZSBTAVSA-N
SMILESC=C1C[C@](OC)([C@H](O)C(=O)NC2OCO[C@H]3[C@@H]2O[C@H](CC(O)CO)C(C)(C)[C@@H]3OC)O[C@H](C)[C@@H]1C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:10345974, npatlas:NPA028635

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 0

None. The compound has a characterized gene cluster whose host NCBI does not name, which for an uncultured symbiont is the honest state — see the discussion below.

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002055 not named CLUSTER_UNSTATED genbank:JAAHTG010000029.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

unnamed-producer — No producer claim is written from BGC0002055, which gives NCBITaxon:1163772 (under metagenomes — a community, not an organism), because the taxon names no single organism. The cluster is kept: a characterized locus is an origin assertion whether or not its host has a name, and for a compound from an uncultured symbiont that is the honest state. Name the producer if the primary literature does.

Provenance

Source conceptSourceVersion
BGC0002055MIBIG3

This page is generated from data/natural_products/polyketides/mycalamide-a.yaml, which is generated from the committed inventories. Neither is edited by hand.