mycolactone B
naturalproductmech:mibig-7a791b74f3 MINTED SEEDED
Structure
| Standard InChIKey | WKTLNJXZVDLRTJ-PCNYYULESA-N |
|---|---|
| SMILES | C[C@@H](O)C[C@@H](O)[C@H](C)\C=C(/C)C[C@H](C)[C@H]1C\C=C(C)/C[C@H](C)[C@H](CCCC(=O)O1)OC(=O)\C=C\C(\C)=C\C(\C)=C\C=C\C(\C)=C\[C@H](O)[C@@H](O)C[C@H](C)O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA019693 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Mycobacterium ulcerans Agy99 NCBITaxon:362242 |
SOURCE_ASSERTION | mibig:BGC0000103 | PMID:14736915 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Mycobacterium ulcerans NCBITaxon:1809 |
LOTUS | DOI:10.1021/JA990017L |
| Mycobacterium ulcerans NCBITaxon:1809 |
LOTUS | DOI:10.1073/PNAS.0305877101 |
| Mycobacterium ulcerans NCBITaxon:1809 |
LOTUS | DOI:10.3987/COM-01-9199 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000103 | Mycobacterium ulcerans Agy99 NCBITaxon:362242 |
CLUSTER_UNSTATED | genbank:BX649209.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000103 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/mycolactone-b.yaml, which is generated from the committed inventories. Neither is edited by hand.