NaturalProductMech

naphthalene-1,3,8-triol

CHEBI:18393 EXACT SEEDED

A naphthalenetriol that is naphthalene substituted by hydroxy groups at positions 1, 3 and 8.

Structure

Standard InChIKeyUSWUTUCXLQBQCG-UHFFFAOYSA-N
SMILESOC1=C2C(C=CC=C2O)=CC(O)=C1
Stereochemistryfully defined

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Pestalotiopsis fici W106-1
NCBITaxon:1229662
BGC_CORRELATED mibig:BGC0002161 PMID:28517364

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Aspergillus fumigatus
NCBITaxon:746128
LOTUS DOI:10.1080/13693780802307720

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002161 Pestalotiopsis fici W106-1
NCBITaxon:1229662
CLUSTER_DEMONSTRATED genbank:KI912112.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

name-disagreement — ChEBI calls this structure 'naphthalene-1,3,8-triol' and MIBiG calls it 'T3HN'. They share a Standard InChIKey, so if the names denote different compounds then one upstream record has the wrong structure. Check which.

Provenance

Source conceptSourceVersion
BGC0002161MIBIG2
CHEBI:18393CHEBI3-star

This page is generated from data/natural_products/polyketides/naphthalene-1-3-8-triol.yaml, which is generated from the committed inventories. Neither is edited by hand.