naphthomycin A
naturalproductmech:mibig-efdb010171 MINTED SEEDED
Structure
| Standard InChIKey | AXEGRHYJHHPVDH-UMKVKWLOSA-N |
|---|---|
| SMILES | C[C@H]1\C=C\C=C/C=C(C)\C(=O)NC2=C(Cl)C(=O)C3=C(C=C(C)C(O)=C3C(=O)\C(C)=C\[C@H](C)[C@@H](O)[C@@H](C)\C=C\[C@@H](O)C\C=C(C)\C(=O)C[C@@H]1O)C2=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA0326 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. CS NCBITaxon:876169 |
BGC_CHARACTERIZED | mibig:BGC0000106 | PMID:21614382 |
Occurrences 7
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/ACS.JNATPROD.6B01059 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/NP300109S |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1039/C1MB05036B |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.7164/ANTIBIOTICS.28.85 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.7164/ANTIBIOTICS.38.948 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.7164/ANTIBIOTICS.51.845 |
| Streptomyces collinus NCBITaxon:42684 |
LOTUS | DOI:10.1139/V94-028 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000106 | Streptomyces sp. CS NCBITaxon:876169 |
CLUSTER_DEMONSTRATED | genbank:GQ452266.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000106 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/naphthomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.