α naphtocyclinoic acid
naturalproductmech:mibig-216aae818e MINTED SEEDED
Structure
| Standard InChIKey | HSAYNVFLMRITQH-BRZSWXGTSA-N |
|---|---|
| SMILES | C[C@H](O1)C2=C(O)C(C([C@@H]3C[C@@]4(OC(C)=O)C5=C3C(O)=C(C(C(O)=C(CC(O)CC(O)=O)C6=O)=O)C6=C5O)=O)=C4C=C2C[C@@H]1CC(O)=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces arenae DSM 40737 NCBITaxon:29301 |
SOURCE_ASSERTION | mibig:BGC0000248 | PMID:10206788 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces arenae NCBITaxon:29301 |
LOTUS | DOI:10.1016/S0378-1119(98)00618-0 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000248 | Streptomyces arenae DSM 40737 NCBITaxon:29301 |
CLUSTER_DEMONSTRATED | genbank:JAKQYH010000014.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000248 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/naphtocyclinoic-acid.yaml, which is generated from the committed inventories. Neither is edited by hand.