nargenicin A1
naturalproductmech:mibig-d46da6eaa2 MINTED SEEDED
Structure
| Standard InChIKey | YEUSSARNQQYBKH-SIMZXIQRSA-N |
|---|---|
| SMILES | C[C@@H]1/C=C(/[C@]23[C@@H](C[C@@H](C(=O)O[C@@H]1[C@@H](C)O)OC)C=C[C@@H]4[C@H]2[C@@H]([C@H]([C@H]([C@@H]4O3)OC(=O)C5=CC=CN5)C)O)\C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:6326334 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 0
None. The compound has a characterized gene cluster whose host NCBI does not name, which for an uncultured symbiont is the honest state — see the discussion below.
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001875 | not named | CLUSTER_DEMONSTRATED | genbank:MN095516.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
unnamed-producer — No producer claim is written from BGC0001875, which gives NCBITaxon:12908 (NCBI's bin for unclassified sequences), because the taxon names no single organism. The cluster is kept: a characterized locus is an origin assertion whether or not its host has a name, and for a compound from an uncultured symbiont that is the honest state. Name the producer if the primary literature does.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001875 | MIBIG | 4 |
This page is generated from data/natural_products/polyketides/nargenicin-a1-2.yaml, which is generated from the committed inventories. Neither is edited by hand.