NaturalProductMech

nargenicin A1

naturalproductmech:mibig-6437746e58 MINTED SEEDED

Structure

Standard InChIKeyYEUSSARNQQYBKH-KFIBIINQSA-N
SMILESO=C2O[C@H]([C@H](O)C)[C@@H](\C=C(/C)[C@]51O[C@H]4[C@H](\C=C/[C@@H]1C[C@@H]2OC)[C@H]5[C@H](O)[C@H]([C@H]4OC(=O)c3ccc[nH]3)C)C
Stereochemistryfully defined
Cross-referencespubchem:6326334

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Nocardia argentinensis
NCBITaxon:1311812
SOURCE_ASSERTION mibig:BGC0002024 PMID:30867595
Nocardia argentinensis
NCBITaxon:1311812
SOURCE_ASSERTION mibig:BGC0002024 PMID:30867595

Occurrences 0

None cited.

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002024 Nocardia argentinensis
NCBITaxon:1311812
CLUSTER_UNSTATED genbank:MH544245.1
mibig:BGC0002024 Nocardia argentinensis
NCBITaxon:1311812
CLUSTER_UNSTATED genbank:MH544245.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002024MIBIG3
BGC0002024MIBIG3

This page is generated from data/natural_products/polyketides/nargenicin-a1.yaml, which is generated from the committed inventories. Neither is edited by hand.