necroxime A
naturalproductmech:mibig-942dcb1c8b MINTED SEEDED
Structure
| Standard InChIKey | DCGOFMMAYQGADN-RKCJKIKXSA-N |
|---|---|
| SMILES | CON=CC=CC(=O)NC=CC[C@H]1C[C@@H](OC(=O)[C@H](CCCCN)NC(=O)C[C@@H](C)O)[C@H]2O[C@H]2[C@@H](O)C=CC2=C(C(=O)O1)C(O)=CC=C2 |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA031543 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Burkholderia sp. B8(2020) NCBITaxon:2713619 |
BGC_CHARACTERIZED | mibig:BGC0002050 | DOI:10.1002/anie.201916007 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Burkholderia NCBITaxon:32008 |
LOTUS | DOI:10.1002/ANIE.201916007 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002050 | Burkholderia sp. B8(2020) NCBITaxon:2713619 |
CLUSTER_DEMONSTRATED | genbank:MN734804.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002050 | MIBIG | 3 |
This page is generated from data/natural_products/polyketides/necroxime-a.yaml, which is generated from the committed inventories. Neither is edited by hand.