NaturalProductMech

nectriapyrone D

CHEBI:142799 EXACT SEEDED

A member of the class of nectriapyrones that is nectriapyrone that carries a hydroxy group at position 4. It is a fungal metabolite isolated from Diaporthe gulyae.

Structure

Standard InChIKeyDDLZRFCVVWLJQN-QPJJXVBHSA-N
SMILESCOC1=C(C)C(=O)OC(/C(C)=C/CO)=C1
Stereochemistryfully defined
Cross-referencesnpatlas:NPA032464, pubchem:135563708

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Pyricularia oryzae 70-15
NCBITaxon:242507
BGC_CHARACTERIZED mibig:BGC0002155 PMID:30443971

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Diaporthe gulyae
NCBITaxon:1116854
CHEBI PMID:25700035
Nectria
NCBITaxon:5133
LOTUS DOI:10.1080/10286020.2015.1040778

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002155 Pyricularia oryzae 70-15
NCBITaxon:242507
CLUSTER_DEMONSTRATED genbank:CM001235.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002155MIBIG3
CHEBI:142799CHEBI3-star

This page is generated from data/natural_products/polyketides/nectriapyrone-d.yaml, which is generated from the committed inventories. Neither is edited by hand.