niphimycin Iα
naturalproductmech:mibig-94762f8b7b MINTED SEEDED
Structure
| Standard InChIKey | VAYOSPAPALLOIO-IVEPKIRNSA-N |
|---|---|
| SMILES | CN=C(N)NCCC/C=C/CCC[C@H](C)C[C@H](C)[C@H]1OC(=O)[C@H](C)[C@H](O)/C=C/[C@H](C)[C@H](O)C[C@H](O)[C@H](C)[C@@H](O)CC[C@H](C)[C@H](O)C[C@]2(O)O[C@H](C[C@@H](OC(=O)CC(=O)O)C[C@H](O)C[C@@H](O)[C@H](C)[C@H](O)/C=C/C=C/[C@@H]1C)C[C@H](O)[C@H]2O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA032427 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. IMB7-145 NCBITaxon:2070498 |
SOURCE_ASSERTION | mibig:BGC0001700 | PMID:29308897 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/ACS.JNATPROD.7B00859 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001700 | Streptomyces sp. IMB7-145 NCBITaxon:2070498 |
CLUSTER_UNSTATED | genbank:MF671979.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001700 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/niphimycin-i.yaml, which is generated from the committed inventories. Neither is edited by hand.