NaturalProductMech

nystatin

naturalproductmech:mibig-abcb52a0e3 MINTED SEEDED antifungal

Structure

Standard InChIKeyVQOXZBDYSJBXMA-RKEBNKJGSA-N
SMILESC[C@H]1/C=C/C=C/CC/C=C/C=C/C=C/C=C/C(CC2C(C(C[C@](O2)(CC(C(CCC(CC(CC(CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces albulus
NCBITaxon:1971
SOURCE_ASSERTION mibig:BGC0001709 DOI:10.3389/fmicb.2018.02550

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces albulus
NCBITaxon:1971
LOTUS DOI:10.3389/FMICB.2018.02550

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001709 Streptomyces albulus
NCBITaxon:1971
CLUSTER_UNSTATED genbank:MG742725.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

Provenance

Source conceptSourceVersion
BGC0001709MIBIG5

This page is generated from data/natural_products/polyketides/nystatin.yaml, which is generated from the committed inventories. Neither is edited by hand.