oxytetracycline
naturalproductmech:mibig-fa820c0e90 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | FYDOORKXBWEKQM-GUQPPTOYSA-N |
|---|---|
| SMILES | C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)/C(=C(\N)/O)/C(=O)[C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)N(C)C)O)O |
| Stereochemistry | fully defined |
| Cross-references | pubchem:5280972 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces rimosus NCBITaxon:1927 |
SOURCE_ASSERTION | mibig:BGC0000254 | PMID:16597959 |
Occurrences 25
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/BF02876994 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-018-8793-Z |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S11427-017-9121-4 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/0378-1119(94)90144-9 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/J.JBIOSC.2012.07.020 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/S1074-5521(97)90233-7 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1074/JBC.M503191200 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1111/J.1365-2672.1996.TB03255.X |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1128/AEM.41.2.366-370.1981 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1128/AEM.67.1.239-244.2001 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1128/GENOMEA.00517-14 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1128/JB.161.3.1010-1016.1985 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1271/BBB.59.1360 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1007/BF02876994 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1007/S00253-018-8793-Z |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1007/S11427-017-9121-4 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1016/0378-1119(94)90144-9 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1016/J.JBIOSC.2012.07.020 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1016/S1074-5521(97)90233-7 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1074/JBC.M503191200 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1111/J.1365-2672.1996.TB03255.X |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1128/AEM.41.2.366-370.1981 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1128/AEM.67.1.239-244.2001 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1128/GENOMEA.00517-14 |
| Kitasatospora aureofaciens NCBITaxon:1894 |
LOTUS | DOI:10.1128/JB.161.3.1010-1016.1985 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000254 | Streptomyces rimosus NCBITaxon:1927 |
CLUSTER_UNSTATED | genbank:DQ143963.2 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000254 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/oxytetracycline.yaml, which is generated from the committed inventories. Neither is edited by hand.