phthoxazolin
naturalproductmech:mibig-8c9a7c64ac MINTED SEEDED
Structure
| Standard InChIKey | MRTUFVRJHFZVOT-FJOYPXEJSA-N |
|---|---|
| SMILES | C\C(=C\C=C/C=C/CC1=CN=CO1)[C@@H](O)C(C)(C)C(N)=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA06501 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces avermitilis NCBITaxon:33903 |
SOURCE_ASSERTION | mibig:BGC0001740 | PMID:29324854 |
Occurrences 5
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.7164/ANTIBIOTICS.46.1214 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.7164/ANTIBIOTICS.46.1699 |
| Streptomyces avermitilis NCBITaxon:33903 |
LOTUS | DOI:10.1016/J.JBIOSC.2017.06.014 |
| Streptomyces avermitilis NCBITaxon:33903 |
LOTUS | DOI:10.1371/JOURNAL.PONE.0190973 |
| Streptomyces avermitilis NCBITaxon:33903 |
LOTUS | DOI:10.7164/ANTIBIOTICS.43.1034 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001740 | Streptomyces avermitilis NCBITaxon:33903 |
CLUSTER_UNSTATED | genbank:LC315614.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001740 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/phthoxazolin.yaml, which is generated from the committed inventories. Neither is edited by hand.