polyketomycin
naturalproductmech:mibig-96ff336a6a MINTED SEEDED
Structure
| Standard InChIKey | OWRCRVABZYJUES-AWECJWJISA-N |
|---|---|
| SMILES | COC1=CC(=O)C2=C(C(C)=C3CC4(O)C(O[C@H]5CC[C@H](O[C@H]6C[C@@](C)(O)[C@H](OC(=O)C7=C(C)C=CC(C)=C7O)[C@H](C)O6)[C@@H](C)O5)C(=O)\C(=C(\C)O)C(=O)C4(O)C(=O)C3=C2O)C1=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | CHEBI:66771, npatlas:NPA01096 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces diastatochromogenes NCBITaxon:42236 |
BGC_CHARACTERIZED | mibig:BGC0001061 | DOI:10.7164/antibiotics.51.26 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces diastatochromogenes NCBITaxon:42236 |
LOTUS | DOI:10.7164/ANTIBIOTICS.51.21 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001061 | Streptomyces diastatochromogenes NCBITaxon:42236 |
CLUSTER_DEMONSTRATED | genbank:FJ483966.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
structure-disagreement — MIBiG cross-references this compound to CHEBI:66771, but ChEBI holds CHEBI:66771 with Standard InChIKey OWRCRVABZYJUES-FLJLGRLJSA-N and this record's structure is OWRCRVABZYJUES-AWECJWJISA-N. The skeleton blocks match, so the two disagree about stereochemistry: check which configuration the primary literature supports.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001061 | MIBIG | 4 |
This page is generated from data/natural_products/polyketides/polyketomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.