ravidomycin
CHEBI:84037 EXACT SEEDED antimicrobial unspecified
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
A C-glycosylated naphthoisochromene derivative obtained from Streptomyces ravidus; exhibits antibiotic and anticancer properties.
Structure
| Standard InChIKey | GHLIFBNIGXVDHM-VQXSZRIGSA-N |
|---|---|
| SMILES | C[C@@H]1[C@@H]([C@@H]([C@H](C(O1)C2=C3C(=C(C=C2)O)C(=CC4=C3OC(=O)C5=CC(=CC(=C54)OC)C=C)OC)O)N(C)C)OC(=O)C |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:126647 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces ravidus NCBITaxon:691266 |
SOURCE_ASSERTION | mibig:BGC0000263 | PMID:20140934 |
Occurrences 6
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces ravidus NCBITaxon:691266 |
LOTUS | DOI:10.1016/S0040-4039(00)99854-X |
| Streptomyces ravidus NCBITaxon:691266 |
LOTUS | DOI:10.1021/JO00287A031 |
| Streptomyces ravidus NCBITaxon:691266 |
LOTUS | DOI:10.1139/V81-438 |
| Streptomyces ravidus NCBITaxon:691266 |
LOTUS | DOI:10.7164/ANTIBIOTICS.36.355 |
| Streptomyces ravidus NCBITaxon:691266 |
LOTUS | DOI:10.7164/ANTIBIOTICS.42.347 |
| Streptomyces ravidus NCBITaxon:691266 |
CHEBI | PMID:20140934 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000263 | Streptomyces ravidus NCBITaxon:691266 |
CLUSTER_UNSTATED | genbank:FN565485.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Elsewhere in the fleet
- AntibioticMech — CHEBI:84037 (same structure, same inchikey)
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000263 | MIBIG | 5 |
| CHEBI:84037 | CHEBI | 3-star |
This page is generated from data/natural_products/polyketides/ravidomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.