reedsmycin E
CHEBI:219386 EXACT SEEDED antifungal
A macrolide isolated from the reed rhizosphere soil-derived Streptomyces sp. CHQ-64.
Structure
| Standard InChIKey | XVBIZWCWDZDOMC-ZIDJWUOVSA-N |
|---|---|
| SMILES | CCC(C)C1OC(=O)/C=C/C=C\C=C\C=C/C=C/CC(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC(O)/C=C/C1C |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA028433 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. NCBITaxon:1931 |
SOURCE_ASSERTION | mibig:BGC0001755 | DOI:10.1039/c4ra15415k |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1039/C4RA15415K |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1186/S12934-018-0943-6 |
| Streptomyces sp. NCBITaxon:1931 |
CHEBI | 10.1039/c4ra15415k |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001755 | Streptomyces sp. NCBITaxon:1931 |
CLUSTER_UNSTATED | genbank:MG947597.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:219386 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001755 | MIBIG | 5 |
| CHEBI:219386 | CHEBI | 3-star |
This page is generated from data/natural_products/polyketides/reedsmycin-e.yaml, which is generated from the committed inventories. Neither is edited by hand.