salinipyrone A

CHEBI:156357 EXACT SEEDED

A member of the class of 2-pyranones that is 2H-pyran-2-one in which the hydrogens at positions 3, 4, 5 and 6 are replaced by methyl, hydroxy, methyl and (1E,3E,5S,6R)-6-hydroxy-3,5-dimethylocta-1,3-dienyl groups, respectively. It is a polyketide isolated from the marine actinomycete Salinispora pacifica.

Structure

Standard InChIKey	ZAMAVOUZTQYUMR-MHQRDTTCSA-N
SMILES	CC[C@@H](O)[C@@H](C)\C=C(/C)\C=C\C1=C(C)C(O)=C(C)C(=O)O1
Stereochemistry	fully defined
Cross-references	npatlas:NPA013843

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Salinispora pacifica NCBITaxon:351187	SOURCE_ASSERTION	mibig:BGC0001830	PMID:25930739

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Salinispora pacifica NCBITaxon:351187	LOTUS	DOI:10.1021/NP0705155
Salinispora pacifica NCBITaxon:351187	CHEBI	PMID:18321059

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0001830	Salinispora pacifica NCBITaxon:351187	CLUSTER_UNSTATED	genbank:KP997155.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source concept	Source	Version
BGC0001830	MIBIG	3
CHEBI:156357	CHEBI	3-star

This page is generated from data/natural_products/polyketides/salinipyrone-a.yaml, which is generated from the committed inventories. Neither is edited by hand.