NaturalProductMech

salinomycin

naturalproductmech:mibig-90cc844890 MINTED SEEDED

Structure

Standard InChIKeyKQXDHUJYNAXLNZ-SDCJTGBBSA-N
SMILESCC[C@H]([C@@H]1[C@H](C[C@H]([C@@]2(O1)C=C[C@H]([C@]3(O2)CC[C@@](O3)(C)[C@H]4CC[C@@]([C@@H](O4)C)(CC)O)O)C)C)C(=O)[C@@H](C)[C@H]([C@H](C)[C@H]5[C@H](CCC(O5)[C@@H](CC)C(=O)O)C)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:72370

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces albus
NCBITaxon:1888
BGC_CHARACTERIZED mibig:BGC0000144 PMID:22156425

Occurrences 12

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1007/BF02879490
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1007/S00253-008-1591-2
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1007/S11427-017-9122-8
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1007/S11427-018-9474-7
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1016/J.JPBA.2005.05.006
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1016/J.YMBEN.2016.02.012
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1017/S0031182018001919
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1038/SREP15081
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1111/J.1574-6968.2000.TB08868.X
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.1128/AEM.06701-11
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.3389/FBIOE.2019.00212
Streptomyces albus
NCBITaxon:1888
LOTUS DOI:10.3390/MD17060347

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000144 Streptomyces albus
NCBITaxon:1888
CLUSTER_DEMONSTRATED genbank:JN033543.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000144MIBIG5

This page is generated from data/natural_products/polyketides/salinomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.