spinosyn D
CHEBI:9232 EXACT SEEDED antimicrobial unspecified
A spinosyn in which the sugar amino and hydroxy groups are globally methylated with an additional methyl substituent attached to the tetracyclic skeleton. One of the two active ingredients of spinosad.
Structure
| Standard InChIKey | RDECBWLKMPEKPM-PSCJHHPTSA-N |
|---|---|
| SMILES | CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C |
| Stereochemistry | fully defined |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Saccharopolyspora spinosa NCBITaxon:60894 |
SOURCE_ASSERTION | mibig:BGC0000148 | DOI:10.1016/s0040-4039(00)93474-9 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Gossypium NCBITaxon:3633 |
LOTUS | DOI:10.1021/JF960219Q |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000148 | Saccharopolyspora spinosa NCBITaxon:60894 |
CLUSTER_UNSTATED | genbank:AY007564.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:9232 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000148 | MIBIG | 3 |
| CHEBI:9232 | CHEBI | 3-star |
This page is generated from data/natural_products/polyketides/spinosyn-d.yaml, which is generated from the committed inventories. Neither is edited by hand.