spiramycin
naturalproductmech:mibig-f926c1568d MINTED SEEDED
Structure
| Standard InChIKey | ACTOXUHEUCPTEW-JMRHEKERSA-N |
|---|---|
| SMILES | C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)OC4CCC(C(O4)C)N(C)C |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:6419898 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces ambofaciens ATCC 23877 NCBITaxon:278992 |
SOURCE_ASSERTION | mibig:BGC0002033 | PMID:18048924 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces ambofaciens NCBITaxon:1889 |
LOTUS | DOI:10.1016/0141-0229(82)90005-9 |
| Streptomyces ambofaciens NCBITaxon:1889 |
LOTUS | DOI:10.1099/MIC.0.2007/009746-0 |
| Streptomyces albofaciens NCBITaxon:66866 |
LOTUS | DOI:10.1139/M95-021 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002033 | Streptomyces ambofaciens ATCC 23877 NCBITaxon:278992 |
CLUSTER_UNSTATED | genbank:NZ_CP012382.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002033 | MIBIG | 4 |
This page is generated from data/natural_products/polyketides/spiramycin.yaml, which is generated from the committed inventories. Neither is edited by hand.