stambomycin A
naturalproductmech:mibig-6b177781f6 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | NPSHCJDYXPRAHR-MPUABNDYSA-N |
|---|---|
| SMILES | O=C(OC(/C=C/C(O)CC(CCCC(C(C1O)C)O)O)C)CC2(O)OC(C[C@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]3O)C2C)C(C)C(O)/C(C)=C/C=C/CC(O)C(C)C(O)CCCC(O)CC(O)/C(C)=C/C(C(O)C(O)CCC(C)CC(O)CC(O)C(C)CC1)CCCC(CC)C |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces ambofaciens ATCC 23877 NCBITaxon:278992 |
BGC_CHARACTERIZED | mibig:BGC0000151 | PMID:21444795 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces ambofaciens NCBITaxon:1889 |
LOTUS | DOI:10.1073/PNAS.1019077108 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000151 | Streptomyces ambofaciens ATCC 23877 NCBITaxon:278992 |
CLUSTER_DEMONSTRATED | genbank:AM238664.2 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000151 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/stambomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.