NaturalProductMech

tautomycin

naturalproductmech:mibig-5bee3b54de MINTED SEEDED

Structure

Standard InChIKeyRFCWHQNNCOJYTR-QKIDKDKQSA-N
SMILESC[C@@H]1CC[C@@]2(CC[C@@H]([C@@H](O2)[C@H](C)CC[C@@H]([C@H](C)C(=O)C[C@H]([C@@H]([C@@H](C(C)C)OC(=O)C[C@H](C3=C(C(=O)OC3=O)C)O)OC)O)O)C)O[C@H]1CC[C@H](C)C(=O)C
Stereochemistryfully defined
Cross-referencespubchem:3034761

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces spiroverticillatus
NCBITaxon:67366
BGC_CHARACTERIZED mibig:BGC0000159 PMID:16707708

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.7164/ANTIBIOTICS.51.963
Streptomyces spiroverticillatus
NCBITaxon:67366
LOTUS DOI:10.1128/JB.00172-06

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000159 Streptomyces spiroverticillatus
NCBITaxon:67366
CLUSTER_DEMONSTRATED genbank:EF990140.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000159MIBIG5

This page is generated from data/natural_products/polyketides/tautomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.