NaturalProductMech

tetarimycin B

naturalproductmech:mibig-72b5d4d23d MINTED SEEDED

Structure

Standard InChIKeyNUPKBVWVJRTNCS-UHFFFAOYSA-N
SMILESCC1(O)CC(O)CC2=CC3=C(C(O)=C12)C(=O)C1=C(O)C=C(O)C=C1C3(C)C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA06659

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 0

None. The compound has a characterized gene cluster whose host NCBI does not name, which for an uncultured symbiont is the honest state — see the discussion below.

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000274 not named CLUSTER_DEMONSTRATED genbank:JX843821.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

unnamed-producer — No producer claim is written from BGC0000274, which gives NCBITaxon:77133 (uncultured bacterium — shared by every unplaced bacterium), because the taxon names no single organism. The cluster is kept: a characterized locus is an origin assertion whether or not its host has a name, and for a compound from an uncultured symbiont that is the honest state. Name the producer if the primary literature does.

Provenance

Source conceptSourceVersion
BGC0000274MIBIG5

This page is generated from data/natural_products/polyketides/tetarimycin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.