tetranactin
naturalproductmech:mibig-35b4c58b5a MINTED SEEDED
Structure
| Standard InChIKey | NKNPHSJWQZXWIX-DCVDGXQQSA-N |
|---|---|
| SMILES | CC[C@H]1C[C@@H]2CC[C@@H](O2)[C@H](C(=O)O[C@@H](C[C@H]3CC[C@H](O3)[C@@H](C(=O)O[C@H](C[C@@H]4CC[C@@H](O4)[C@H](C(=O)O[C@@H](C[C@H]5CC[C@H](O5)[C@@H](C(=O)O1)C)CC)C)CC)C)CC)C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:441165 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces griseus subsp. griseus NCBITaxon:67263 |
SOURCE_ASSERTION | mibig:BGC0000243 | PMID:10858335 |
| Streptomyces griseus subsp. griseus NCBITaxon:67263 |
SOURCE_ASSERTION | mibig:BGC0000244 | PMID:10858335 |
Occurrences 5
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces globisporus NCBITaxon:1908 |
LOTUS | DOI:10.1007/BF02884062 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1039/P19880001719 |
| Streptomyces araujoniae NCBITaxon:544311 |
LOTUS | DOI:10.1007/S10534-014-9709-8 |
| Streptomyces araujoniae NCBITaxon:544311 |
LOTUS | DOI:10.1080/14786419.2016.1217203 |
| Streptomyces araujoniae NCBITaxon:544311 |
LOTUS | DOI:10.1094/PHYTO-11-13-0327-R |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000243 | Streptomyces griseus subsp. griseus NCBITaxon:67263 |
CLUSTER_UNSTATED | genbank:AF263011.1 |
| mibig:BGC0000244 | Streptomyces griseus subsp. griseus NCBITaxon:67263 |
CLUSTER_UNSTATED | genbank:AF263012.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000243, BGC0000244. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000243 | MIBIG | 4 |
| BGC0000244 | MIBIG | 4 |
This page is generated from data/natural_products/polyketides/tetranactin.yaml, which is generated from the committed inventories. Neither is edited by hand.