tetronomycin
naturalproductmech:mibig-52cc098496 MINTED SEEDED antibacterial
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | PYNSBUJNGRHFPI-REIOUMPOSA-M |
|---|---|
| SMILES | C[C@H]1CCC[C@H]([C@@H]1[C@@H](C)C(=O)C2=C(C(=C)OC2=O)[O-])/C=C(\CO)/[C@@H]3[C@H](CC[C@@H](O3)/C=C/C[C@@H]4CC[C@H](O4)[C@@H](C)OC)C.[Na+] |
| Stereochemistry | fully defined |
| Cross-references | pubchem:44472823 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. NRRL 11266 NCBITaxon:299254 |
SOURCE_ASSERTION | mibig:BGC0000164 | PMID:18404760 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000164 | Streptomyces sp. NRRL 11266 NCBITaxon:299254 |
CLUSTER_UNSTATED | genbank:AB193609.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Elsewhere in the fleet
- AntibioticMech — antibioticmech:aro-8013b9b55a (same structure, same inchikey)
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000164 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/tetronomycin.yaml, which is generated from the committed inventories. Neither is edited by hand.