thailanstatin A
naturalproductmech:mibig-e9796bbf63 MINTED SEEDED
Structure
| Standard InChIKey | GJKQDOMCDFJANR-FUDLAKRJSA-N |
|---|---|
| SMILES | C[C@H](OC(C)=O)\C=C/C(=O)N[C@@H]1C[C@H](C)[C@H](C\C=C(/C)\C=C\[C@H]2O[C@H](CC(O)=O)C[C@@]3(CO3)[C@@H]2O)O[C@@H]1C |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA08640, pubchem:71665768 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Burkholderia thailandensis NCBITaxon:57975 |
SOURCE_ASSERTION | mibig:BGC0001114 | PMID:23517093 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Burkholderia NCBITaxon:32008 |
LOTUS | DOI:10.1021/NP500342M |
| Burkholderia thailandensis NCBITaxon:57975 |
LOTUS | DOI:10.1021/NP300913H |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001114 | Burkholderia thailandensis NCBITaxon:57975 |
CLUSTER_UNSTATED | genbank:JX307851.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001114 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/thailanstatin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.