trioxacarcin A
naturalproductmech:mibig-21e059f035 MINTED SEEDED
Structure
| Standard InChIKey | VVCYZYSLUSSELI-NVJOEFDOSA-N |
|---|---|
| SMILES | C[C@H]1[C@H]([C@](C[C@@H](O1)O[C@H]2C[C@@H](C(=O)C3=C(C4=C(C=C(C5=C4O[C@@]6([C@@H]7[C@H]5O[C@]([C@]68CO8)(O7)C(OC)OC)O[C@H]9C[C@H]([C@]([C@@H](O9)C)(C(=O)C)O)O)C)C(=C23)OC)O)O)(C)O)OC(=O)C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:49799758, chembl:CHEMBL1171076 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces bottropensis DO-45 NCBITaxon:42235 |
BGC_CHARACTERIZED | mibig:BGC0002141 | PMID:30151879 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces bottropensis NCBITaxon:42235 |
LOTUS | DOI:10.1007/S00284-015-0868-9 |
| Streptomyces bottropensis NCBITaxon:42235 |
LOTUS | DOI:10.7164/ANTIBIOTICS.34.1519 |
| Streptomyces bottropensis NCBITaxon:42235 |
LOTUS | DOI:10.7164/ANTIBIOTICS.34.1525 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002141 | Streptomyces bottropensis DO-45 NCBITaxon:42235 |
CLUSTER_DEMONSTRATED | genbank:KP410250.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002141 | MIBIG | 3 |
This page is generated from data/natural_products/polyketides/trioxacarcin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.