NaturalProductMech

urdamycin

naturalproductmech:mibig-d03621b0c2 MINTED SEEDED

Structure

Standard InChIKeyWDNBUGBJVRAIKE-JGRVRNPESA-N
SMILESC[C@H]1[C@H](CC[C@@H](O1)O[C@]23C(=O)C[C@](C[C@]2(C(=CC4=C3C(=O)C5=C(C4=O)C(=C(C=C5)[C@H]6C[C@H]([C@@H]([C@H](O6)C)O)O[C@H]7CC[C@@H]([C@@H](O7)C)O[C@H]8C[C@H]([C@@H]([C@H](O8)C)O)O)O)SC)O)(C)O)O
Stereochemistryfully defined
Cross-referencespubchem:175975

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces fradiae
NCBITaxon:1906
SOURCE_ASSERTION mibig:BGC0000277 PMID:10658661
Streptomyces fradiae
NCBITaxon:1906
SOURCE_ASSERTION mibig:BGC0000278 PMID:11094336

Occurrences 4

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces fradiae
NCBITaxon:1906
LOTUS DOI:10.1039/C39890000492
Streptomyces fradiae
NCBITaxon:1906
LOTUS DOI:10.1099/00221287-146-1-147
Streptomyces fradiae
NCBITaxon:1906
LOTUS DOI:10.7164/ANTIBIOTICS.39.1657
Streptomyces fradiae
NCBITaxon:1906
LOTUS DOI:10.7164/ANTIBIOTICS.40.459

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0000277 Streptomyces fradiae
NCBITaxon:1906
CLUSTER_UNSTATED genbank:AF164961.1
mibig:BGC0000278 Streptomyces fradiae
NCBITaxon:1906
CLUSTER_UNSTATED genbank:AF269227.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000277, BGC0000278. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000277MIBIG5
BGC0000278MIBIG3

This page is generated from data/natural_products/polyketides/urdamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.